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Variation in CD8 T cell IFNγ differentiation to strains of Toxoplasma gondii is characterized by small effect QTLs with contribution from ROP16

Kongsomboonvech, Angel K., Laura García-López, Ferdinand Njume, Felipe Rodriguez, Scott P. Souza, Alex Rosenberg, and Kirk D. C. Jensen. 2023. “Variation in CD8 T cell IFNγ differentiation to strains of Toxoplasma gondii is characterized by small effect QTLs with contribution from ROP16”. Frontiers in Cellular and Infection Microbiology.

Paper on ROCTR is published!

Cumulative work from two graduate students, Angel Kongsomboonvech and Laura Garcia-Lopez, in which genetic mapping was employed to understand the parasite strain differences in eliciting CD8 T cell IFNg production to parasite infected cells. Over 120 parasite strains were screened, and ROP16 - a...

The lab has new NIMH funding

Ramen (PI) and our wonderful collaborator at Purdue university –Dr. Emily Dykhuizen (Co-PI)– received a R21 award from NIMH. The funded grant is titled, "BAF complex inhibitors in neuronal development and functions". This award will fund Karen's project where we are studying the role of BAF complex...