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Scott Souza

Person: Ph.D. '16-'21 Research Analysist, Becton and Dickinson

Graduated from California State University Channel Islands, and then obtained a Ph.D. in my lab. Scott investigated how B cells mediate protective immunity to T. gondii, and determined that B-1 cells are important players in the immune response to the parasites. Drinking coffee in Columbia (above)...

Review on Host Forward Genetics in Apicomplexa is published

News: May 10, 2022

Check out our review on all host forward genetic screens that have been performed on Apicomplexa parasite infections in Frontiers in Cellular and Infection Microbiology. Reviewed are the many forward genetic studies over the past several decades that have revealed multiple aspects of host-parasite...

Felipe is heading to Graduate School!

News: September 04, 2020

Felipe Rodriguez, undergraduate researcher then mentored assistant in the Jensen lab, was accepted into UC Davis Graduate School in the Program of Immunology. We are so proud! Congratulations! Our socially distanced going away party below.

More awards! Wow!

News: April 17, 2018

More awards! Wow! At this years 22nd Annual Woods Hole Immunoparasitology Meeting (WHIP) graduate students Angel Kongsomboonvech and Scott Souza win AAI Young Investigator Awards for their oral and poster presentations, respectively. Congrats Angel and Scott!! I imagine there will be more in the...

PD-L1, TIM-3, and CTLA-4 blockade fail to promote resistance to secondary infection with virulent strains of Toxoplasma gondii.

Publication: Journal Article

Splitt, Samantha D., Scott P. Souza, Kristen M. Valentine, Brayan E. Castellanos, Andrew B. Curd, Katrina K. Hoyer, and Kirk D. C. Jensen. 2018. “PD-L1, TIM-3, and CTLA-4 Blockade Fail to Promote Resistance to Secondary Infection With Virulent Strains of Toxoplasma Gondii.”. Infection and Immunity.

De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs.

Publication: Journal Article

Hassan, Mussa A, Mariane B. Melo, Brian Haas, Kirk D. C. Jensen, and Jeroen P. J. Saeij. 2016. “De Novo Reconstruction of the Toxoplasma Gondii Transcriptome Improves on the Current Genome Annotation and Reveals Alternatively Spliced Transcripts and Putative Long Non-Coding RNAs.”. BMC Genomics, no. 13:696.

Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination.

Publication: Journal Article

Jensen, Kirk D. C., Ana Camejo, Mariane B. Melo, Cynthia Cordeiro, Lindsay Julien, Gijsbert M. Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh, Lucy Young, and Jeroen P.J. Saeij. 2015. “Toxoplasma Gondii Superinfection and Virulence During Secondary Infection Correlate With the Exact ROP5/ROP18 Allelic Combination.”. Bio, no. 6(2).

Identification of three novel Toxoplasma gondii rhoptry proteins

Publication: Journal Article

Camejo, Ana, Daniel A. Gold, Diana Lu, Kiva McFetridge, Lindsay Julien, Ninghan Yang, Kirk D. C. Jensen, and Jeroen P.J. Saeij. 2014. “Identification of Three Novel Toxoplasma Gondii Rhoptry Proteins”. International Journal for Parasitology, no. 44(2): 147-60.

Toxoplasma gondii effectors are master regulators of the inflammatory response.

Publication: Journal Article

Melo, Mariane B., Kirk D. C. Jensen, and Jeroen P.J. Saeij. 2011. “Toxoplasma Gondii Effectors Are Master Regulators of the Inflammatory Response.”. Trends in Parasitology, no. 27(11): 487-95.

Thymic maturation determines γδ T cell function, but not their antigen specificities.

Publication: Journal Article

Jensen, Kirk D. C., and Yueh-hsiu Chien. 2009. “Thymic Maturation Determines γδ T Cell Function, But Not Their Antigen Specificities.”. Current Opinions in Immunology . (21(2): 140-45.