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Splitting hares and tortoises: a classification of neuronal immediate early gene transcription based on poised RNA polymerase II

Publication: Journal Article

Saha, RN, and SM Dudek. 2013. “Splitting Hares and Tortoises: A Classification of Neuronal Immediate Early Gene Transcription Based on Poised RNA Polymerase II”. Neuroscience. 247: 175-81.

Merits and Limitations of Studying Neuronal Depolarization-Dependent Processes Using Elevated External Potassium

Publication: Journal Article

Rienecker, KDA, RG Poston, and RN Saha. 2020. “Merits and Limitations of Studying Neuronal Depolarization-Dependent Processes Using Elevated External Potassium”. ASN Neuro 12: DOI: 10.1177/1759091420974807.

2nd edition of the book is published.

News: November 20, 2024

Transcription Regulation by Neuronal Activity. To the Nucleus and Back. 2nd edition. Edited by Ramen Saha and Serena M Dudek. Published by Springer Nature Switzerland. Details in the 'Publication' page.

About Us

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The lab (circa 2023) The Saha laboratory is a venture in neuronal signal transduction, gene transcription and neuroepigenetics. Our research is geared towards understanding signaling, transcriptional, and epigenetic mechanisms of neuronal gene expression and their roles in neurodevelopment...

Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA polymerase II productive elongation

Publication: Journal Article

Cornejo, Karen G, Andie Venegas, Morgan H Sono, Madeline Door, Brenda Gutierrez-Ruiz, Lucy B Karabedian, Supratik G Nandi, et al. 2024. “Activity-Assembled NBAF Complex Mediates Rapid Immediate Early Gene Transcription by Regulating RNA Polymerase II Productive Elongation”. Cell Reports.

Our research article is published in Cell Reports

News: October 15, 2024

Our study, "Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA polymerase II productive elongation", is now published in Cell Reports. See the Publication page for details. This story of activity-assembled nBAF was led by the unbaffled Ms. Karen...

Ryoichi 'Morgan' Sono

Person: Graduate Student

Morgan completed his BS from UC Merced in 2020. Morgan calls California and Japan home.