Paper on ROCTR is published!

title ROCTR

Cumulative work from two graduate students, Angel Kongsomboonvech and Laura Garcia-Lopez, in which genetic mapping was employed to understand the parasite strain differences in eliciting CD8 T cell IFNg production to parasite infected cells. Over 120 parasite strains were screened, and ROP16 - a parasite kinase that activates the alternative activation of macrophages - was found to dampen transcription of IFNg. Lots of work to find Regulator of CD8 T cell Responses (ROCTR), well done.