We are a young lab (we "opened" our doors in summer 2017) and we are mainly interested in the biochemical and structural study of membrane proteins. Currently, we are focused on the study of a family of membrane proteins known as ATP-Binding Cassette (ABC) transporters. The function of these transporters is very diverse, including protecting the cells against toxic molecules, the export of lipids, ions, etc. and it is well known that some members of the ABC family are involved in the development of multi-drug resistance and diseases such as cystic fibrosis. We want to understand, at the molecular level, how these transporters are capable of binding and moving their substrate across membranes and how the activity of these transporters can be modulated by drugs, with the hope that such information will be used for the rational design of therapeutic molecules. The function of many human ABC transporters is still unknown and we expect that our research will contribute to a better understanding of their physiological role.