Peer-Reviewed Publications (≠Graduate student. ^Undergraduate student).
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD≠, Martinez M^, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME*, Carpenter EP*, Liesa M. ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity. Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869. PMID: 34011630. *Equal contribution.
Saxberg AD≠, Martinez M^, Fendley GA, Zoghbi ME. Production of a human mitochondrial ABC transporter in E. coli. Protein Expr Purif. 2021 Feb; 178:105778. doi: 10.1016/j.pep.2020.105778. Epub 2020 Oct 15. PMID: 33069825; PMCID: PMC7709767.
Martinez M^, Fendley GA, Saxberg AD≠, Zoghbi ME. Stimulation of the human mitochondrial transporter ABCB10 by zinc-mesoporphrin. PLoS One. 2020;15(11):e0238754. PubMed Central PMCID: PMC7703921.
Zoghbi ME, Altenberg GA. Luminescence resonance energy transfer spectroscopy of ATP-binding cassette proteins. Biochim Biophys Acta Biomembr. 2018 Apr;1860(4):854-867. doi: 10.1016/j.bbamem.2017.08.005. Epub 2017 Aug 8. PMID: 28801111.
Zoghbi ME, Mok L, Swartz DJ, Singh A, Fendley GA≠, Urbatsch IL, Altenberg GA. Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer-associated P-glycoprotein during ATP hydrolysis. J Biol Chem. 2017 Dec 15;292(50):20412-20424. doi: 10.1074/jbc.M117.814186. Epub 2017 Oct 9. PMID: 29018094; PMCID: PMC5733581.
Zoghbi ME, Altenberg GA. Membrane protein reconstitution in nanodiscs for luminescence spectroscopy studies. Nanotechnology Reviews, vol. 6, no. 1, 2017, pp. 33-46. https://doi.org/10.1515/ntrev-2016-0078.
Fendley GA≠, Urbatsch IL, Sutton RB, Zoghbi ME, Altenberg GA. Nucleotide dependence of the dimerization of ATP binding cassette nucleotide binding domains. Biochem Biophys Res Commun. 2016 Nov 11;480(2):268-272. doi: 10.1016/j.bbrc.2016.10.046. Epub 2016 Oct 17. PMID: 27765627.
Zoghbi ME, Cooper RS≠, Altenberg GA. The Lipid Bilayer Modulates the Structure and Function of an ATP-binding Cassette Exporter. J Biol Chem. 2016 Feb 26;291(9):4453-61. doi: 10.1074/jbc.M115.698498. Epub 2016 Jan 2. PMID: 26725230; PMCID: PMC4813473.
Zoghbi ME, Altenberg GA. ATP binding to two sites is necessary for dimerization of nucleotide-binding domains of ABC proteins. Biochem Biophys Res Commun. 2014 Jan 3;443(1):97-102. doi: 10.1016/j.bbrc.2013.11.050. Epub 2013 Nov 19. PMID: 24269240; PMCID: PMC3901029.
Zoghbi ME, Altenberg GA. Hydrolysis at one of the two nucleotide-binding sites drives the dissociation of ATP-binding cassette nucleotide-binding domain dimers. J Biol Chem. 2013 Nov 22;288(47):34259-34265. doi: 10.1074/jbc.M113.500371. Epub 2013 Oct 15. PMID: 24129575; PMCID: PMC3837166.
Fiori MC, Figueroa V, Zoghbi ME, Saéz JC, Reuss L, Altenberg GA. Permeation of calcium through purified connexin 26 hemichannels. J Biol Chem. 2012 Nov 23;287(48):40826-34. doi: 10.1074/jbc.M112.383281. Epub 2012 Oct 9. PMID: 23048025; PMCID: PMC3504794.
Zoghbi ME, Krishnan S≠, Altenberg GA. Dissociation of ATP-binding cassette nucleotide-binding domain dimers into monomers during the hydrolysis cycle. J Biol Chem. 2012 Apr 27;287(18):14994-5000. doi: 10.1074/jbc.M112.340281. Epub 2012 Mar 8. PMID: 22403405; PMCID: PMC3340254.
Zoghbi ME, Fuson KL, Sutton RB, Altenberg GA. Kinetics of the association/dissociation cycle of an ATP-binding cassette nucleotide-binding domain. J Biol Chem. 2012 Feb 3;287(6):4157-64. doi: 10.1074/jbc.M111.318378. Epub 2011 Dec 9. PMID: 22158619; PMCID: PMC3281709.
Luther PK, Winkler H, Taylor K, Zoghbi ME, Craig R, Padrón R, Squire JM, Liu J. Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11423-8. doi: 10.1073/pnas.1103216108. Epub 2011 Jun 24. PMID: 21705660; PMCID: PMC3136262.
Zoghbi ME, Woodhead JL, Moss RL, Craig R. Three-dimensional structure of vertebrate cardiac muscle myosin filaments. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2386-90. doi: 10.1073/pnas.0708912105. Epub 2008 Feb 5. PMID: 18252826; PMCID: PMC2268146.
Zoghbi ME, Woodhead JL, Craig R, Padrón R. Helical order in tarantula thick filaments requires the "closed" conformation of the myosin head. J Mol Biol. 2004 Sep 24;342(4):1223-36. doi: 10.1016/j.jmb.2004.07.037. PMID: 15351647.
Zoghbi ME, Copello JA, Villalba-Galea CA, Vélez P, Diaz Sylvester PL, Bolaños P, Marcano A, Fill M, Escobar AL. Differential Ca2+ and Sr2+ regulation of intracellular divalent cations release in ventricular myocytes. Cell Calcium. 2004 Aug;36(2):119-34. doi: 10.1016/j.ceca.2004.01.023. PMID: 15193860.
Escobar AL, Ribeiro-Costa R, Villalba-Galea C, Zoghbi ME, Pérez CG, Mejía-Alvarez R. Developmental changes of intracellular Ca2+ transients in beating rat hearts. Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H971-8. doi: 10.1152/ajpheart.00308.2003. Epub 2003 Nov 26. Erratum in: Am J Physiol Heart Circ Physiol. 2004 Jul;56(1):H433. PMID: 14644760.
Zoghbi ME, Bolaños P, Villalba-Galea C, Marcano A, Hernández E, Fill M, Escobar AL. Spatial Ca(2+) distribution in contracting skeletal and cardiac muscle cells. Biophys J. 2000 Jan;78(1):164-73. doi: 10.1016/S0006-3495(00)76582-9. PMID: 10620283; PMCID: PMC1300627.