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Our current research spans three areas: Sequence recognition of transcription factors - Transcription factors (TFs) are proteins that bind specific sites in the genome in order to regulate the expression of nearby genes. This binding, which is stochastic kinetic process, depends on many variables...

H. Tomas Rube Assistant Professor, Department of Applied Mathematics Starting July 2022, H. Tomas Rube is an assistant professor in Applied Mathematics at University of California, Merced. With an undergraduate degree in engineering physics and a PhD in theoretical physics, Tomas’ research lies at...

This page contains a list of computational methods and resources that we have developed. Please do not hessitate to contact us if you have any problems or questions. ProBound - A software that analyzes sequencing data from randomized binding assays in order to learn energetic models of sequence...