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Rube Lab
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines
Zhang, Liyang, John A Zuris, Ramya Viswanathan, Jasmine N Edelstein, Rolf Turk, Bernice Thommandru, Tomas Rube, et al. 2021. “AsCas12a Ultra Nuclease Facilitates the Rapid Generation of Therapeutic Cell Medicines”. Nat. Commun. 12 (1): 4500.
A unified approach for quantifying and interpreting DNA shape readout by transcription factors
Rube, Tomas, Chaitanya Rastogi, Judith F Kribelbauer, and Harmen J Bussemaker. 2018. “A Unified Approach for Quantifying and Interpreting DNA Shape Readout by Transcription Factors”. Mol. Syst. Biol. 14 (2): e7902.
Accurate and sensitive quantification of protein-DNA binding affinity
Rastogi, Chaitanya, Tomas Rube, Judith F Kribelbauer, Justin Crocker, Ryan E Loker, Gabriella D Martini, Oleg Laptenko, et al. 2018. “Accurate and Sensitive Quantification of Protein-DNA Binding Affinity”. Proc. Natl. Acad. Sci. U. S. A. 115 (16): E3692–E3701.
The simplicity of perfect atoms: degeneracies in supersymmetric hydrogen
Rube, Tomas, and Jay G Wacker. 2011. “The Simplicity of Perfect Atoms: Degeneracies in Supersymmetric Hydrogen”. Journal of Mathematical Physics 52 (6): 062102.
Rube Lab Founded
Tomas joins the Applied Mathematics Department at the University of California, Merced as an Assistant Professor.
Research
Our current research spans three areas: Accelerating proteomics research using compressed sensing - Protein-protein interactions (PPIS) are important in governing numerous processes like development and the onset of pathological conditions such as cancer and neurodegenerative disease. PPIs form...
General inflaton potentials in supergravity
Kallosh, Renata, Andrei Linde, and Tomas Rube. 2011. “General Inflaton Potentials in Supergravity”. Physical Review D.
Seminar
Tomas gives the Applied Math Seminar at UC Merced.