SH2 preprint out
The preprint " Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression" is out on bioRxiv.
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Shahram and Moitrish present their work at AM Retreat
Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants.
Zhang, L, G Li, Y Zhang, Y Cheng, N Roberts, SE Glenn, D DeZwaan-McCabe, et al. 2023. “Boosting Genome Editing Efficiency in Human Cells and Plants With Novel LbCas12a Variants.”. Europe PMC.
New funding from NIMH
We received a new R21 award from NIMH. The project is titled, ' The BAF chromatin remodeling complex in experience-induced neuronal gene transcription and synapse maturation; implications for autism spectrum disorder'. The goal of this project is to reveal the role of intrinsically disordered...
Moitrish joins the lab
We would like to welcome Applied Math graduate student Moitrish to the lab!
Teaching
Fall Semester 2022 - MATH 180 - Modern Applied Statistics Fall Semester 2023 - MATH 180 - Modern Applied Statistics Spring Semester 2024 - MATH 32 - Probability and Statistics Fall Semester 2024 - MATH 180 - Applied Statistics and Machine Learning Spring Semester 2025 - MATH 280 - Mathematical and...
Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression
Gagoski, Dejan, Tomas Rube, Chaitanya Rastogi, Lucas AN Melo, Xiaoting Li, Rashmi Voleti, Neel H. Shah, and Harmen J. Bussemaker. Forthcoming. “Accurate Sequence-to-Affinity Models for SH2 Domains from Multi-Round Peptide Binding Assays Coupled With Free-Energy Regression”. BioRxiv, Forthcoming.
Shahram Joins Lab
We would like to welcome Applied Math graduate student Shahram to the lab!
28th Woods Hole Immuno-parasitology meeting - a success!
I was honored to be the lead organizer of the Woods hole Immuno-parasitology ( WHIP) meeting that I co-organized with Tajie Harris (University of Virginia) April 13-16, 2025. We had ground breaking trainee talks, and wonderful key note addresses from P'ng Loke (NIH), Jenny Ting (University of North...
Cas12a Paper Published
The paper " Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants" was published in Europe PMC.