SH2 preprint out
The preprint " Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression" is out on bioRxiv.
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Shahram and Moitrish present their work at AM Retreat
Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants.
Zhang, L, G Li, Y Zhang, Y Cheng, N Roberts, SE Glenn, D DeZwaan-McCabe, et al. 2023. “Boosting Genome Editing Efficiency in Human Cells and Plants With Novel LbCas12a Variants.”. Europe PMC.
SPRINT-MS Preprint
We just put out a preprint describing SPRINT-MS, an integrated computational-experimental platform that uses compressed sensing to accelerate proteomics research! The preprint can be found here.
Candidate Moitrish!
Join us in celebrating that Moitrish passed the Qualifying Exam with flying colors. Hurray!
Resource SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress
Wolin, Erica, Jimmy K. Guo, Mario R. Blanco, Isabel N. Goronzy, Darvesh Gorhe, Wenzhao Dong, Andrew A. Perez, et al. 2025. “Resource SPIDR Enables Multiplexed Mapping of RNA-Protein Interactions and Uncovers a Mechanism for Selective Translational Suppression Upon Cell Stress”. Cell 188.
Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression
Gagoski, Dejan, Tomas Rube, Chaitanya Rastogi, Lucas AN Melo, Xiaoting Li, Rashmi Voleti, Neel H. Shah, and Harmen J. Bussemaker. 2025. “Accurate Sequence-to-Affinity Models for SH2 Domains from Multi-Round Peptide Binding Assays Coupled With Free-Energy Regression”. BioRxiv 34 (11).
Moitrish joins the lab
We would like to welcome Applied Math graduate student Moitrish to the lab!
Teaching
Fall Semester 2022 - MATH 180 - Modern Applied Statistics Fall Semester 2023 - MATH 180 - Modern Applied Statistics Spring Semester 2024 - MATH 32 - Probability and Statistics Fall Semester 2024 - MATH 180 - Applied Statistics and Machine Learning Spring Semester 2025 - MATH 280 - Mathematical and...
Shahram Joins Lab
We would like to welcome Applied Math graduate student Shahram to the lab!