OpenScholar

Search results

35 results found

Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to successive stimulus.

Publication: Journal Article

Rienecker, Kira D A, Robert G Poston, Joshua S Segales, Isabelle W Finholm, Morgan H Sono, Sorina J Munteanu, Mina Ghaninejad-Esfahani, et al. 2022. “Mild Membrane Depolarization in Neurons Induces Immediate Early Gene Transcription and Acutely Subdues Responses to Successive Stimulus”. Journal of Biological Chemistry.

Certain Ortho-Hydroxylated Brominated Ethers Are Promiscuous Kinase Inhibitors That Impair Neuronal Signaling and Neurodevelopmental Processes

Publication: Journal Article

Poston, RG, L Murphy, A Rejepova, M Ghaninejad-Esfahani, J Segales, K Mulligan, and RN Saha. 2020. “Certain Ortho-Hydroxylated Brominated Ethers Are Promiscuous Kinase Inhibitors That Impair Neuronal Signaling and Neurodevelopmental Processes”. Journal of Biological Chemistry.

Genome-wide RNA Pol II Initiation and Pausing in Neural Progenitors of the Rat

Publication: Journal Article

Scheidegger, Adam, Carissa J. Dunn, Ann Samarakkody, Nii Koney-Kwaku Koney, Danielle Perley, Ramendra N. Saha, and Sergei Nechaev. 2019. “Genome-wide RNA Pol II Initiation and Pausing in Neural Progenitors of the Rat”. BMC Genomics 20: 477.

Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes.

Publication: Journal Article

Dunn, Carissa J, Pushpita Sarkar, Emma R Bailey, Shannon Farris, Meilan Zhao, James M Ward, Serena M Dudek, and Ramendra N Saha. 2017. “Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc Arg3.1 and Other Immediate Early Genes”. ENeuro 4: 0040-17.

Saha Lab photos 2022-2023

Page

Purkinje Tattoos. Fall 2022 Isabel and Maddie Campus colors. Fall 2022. Ramen, Karen, Andie, and Morgan Hanging out with Dr. Hayashi. 11/25/2022 Karen, Andie, Ramen, and Morgan with Dr. Hayashi (Kyoto Univ) Karen at SfN. November 2022 Poster presentation at 2023 San Diego SfN annual meeting ...

2023-2024 Senate Research Award

News: March 16, 2023

Ramen was awarded the 2023-24 UC Merced senate award to study a novel inhibitor of the neuronal activity-induced gene transcription. The proposal is titled, 'A study of BAF complex functions in neurons using novel inhibitor '704'.

Karenia Damacio

Person: UROC LAEP Undergraduate Research Fellow

My name is Karenia Damacio, and I am a fourth-year undergraduate student majoring in Molecular and Cell Biology. I joined the Saha lab to gain laboratory experience and to learn more about neural signaling and gene transcription. In my free time, I like to talk to my parents, and watch formula 1.

Latest Preprint from the lab

News: January 01, 2024

We have released our latest preprint, titled: Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA Polymerase II productive elongation. This study was led by Karen Cornejo as a part of her thesis project. Andie Venegas and Morgan Sono were amazing...

Andie Joins The Lab

News: December 14, 2021

Andie Venegas was accepted in the QSB Ph.D. program. Andie has chosen to pursue her Ph.D. with us and will start as a graduate student in Spring of 2022. We are excited to have Andie in the lab as a graduate student (along with Morgan and Karen). Welcome Andie!

Featured in ASBMB Today

News: January 03, 2021

Here's the link to Anna Tancredi's ASBMB Today article about our our recent work ( published in JBC ) on flame retardants. This article is geared towards the general audience.