SH2 preprint out
The preprint " Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression" is out on bioRxiv.
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Shahram and Moitrish present their work at AM Retreat
Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants.
Zhang, L, G Li, Y Zhang, Y Cheng, N Roberts, SE Glenn, D DeZwaan-McCabe, et al. 2023. “Boosting Genome Editing Efficiency in Human Cells and Plants With Novel LbCas12a Variants.”. Europe PMC.
New funding from NIMH
We received a new R21 award from NIMH. The project is titled, ' The BAF chromatin remodeling complex in experience-induced neuronal gene transcription and synapse maturation; implications for autism spectrum disorder'. The goal of this project is to reveal the role of intrinsically disordered...
Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression
Gagoski, Dejan, Tomas Rube, Chaitanya Rastogi, Lucas AN Melo, Xiaoting Li, Rashmi Voleti, Neel H. Shah, and Harmen J. Bussemaker. Forthcoming. “Accurate Sequence-to-Affinity Models for SH2 Domains from Multi-Round Peptide Binding Assays Coupled With Free-Energy Regression”. BioRxiv, Forthcoming.
Moitrish joins the lab
We would like to welcome Applied Math graduate student Moitrish to the lab!
Teaching
Fall Semester 2022 - MATH 180 - Modern Applied Statistics Fall Semester 2023 - MATH 180 - Modern Applied Statistics Spring Semester 2024 - MATH 32 - Probability and Statistics Fall Semester 2024 - MATH 180 - Applied Statistics and Machine Learning Spring Semester 2025 - MATH 280 - Mathematical and...
Registration is open - 28th Woods Hole Immuno-parasitology meeting
Registration is now open for the Woods hole Immuno-parasitology (WHIP) meeting I am organizing with Tajie Harris (UVA). Registration can be accessed here, April 13-16, 2025. Hope to see you there!
Shahram Joins Lab
We would like to welcome Applied Math graduate student Shahram to the lab!
Cas12a Paper Published
The paper " Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants" was published in Europe PMC.