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Editor's Pick mBio - paper on the GPI of T. gondii

Our paper is published on the GPI sidechain of T. gondii. This is the first description of the entire GPI sidechain synthetic pathway for any eukaryotic microbe generated by two enzymes we named PIGJ and PIGE. This is Julia Alvarez' PH.D. dissertation in collaboration with Chris West at University...

Preprint on the GPI sidechain of Toxoplasma is online!

Very excited to share our discovery and characterization of the GPI sidechain sytnthetic pathway in T. gondii. This is a first for any parasite. This is the thesis work by graduate student Julia Alvarez, in collaboration with Christopher West at University of Georgia. Parasites that lack a GPI...

Latest Preprint from the lab

We have released our latest preprint, titled: Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA Polymerase II productive elongation. This study was led by Karen Cornejo as a part of her thesis project. Andie Venegas and Morgan Sono were amazing...