Welcome to The Merg Lab!
Research within the Merg Lab focuses on the design and fabrication of nanoscale materials derived from the self-assembly of sequence-programmable biomolecules (e.g., peptides, proteins, and nucleic acids). Developing these supramolecular architectures with hierarchical physical and chemical control across length-scales - an outstanding challenge within the field of biomolecular self-assembly - is a critical step towards the deployment of these materials for a variety of biomedical and bioengineering applications (e.g., biosensors, drug delivery, catalysis, etc.). The Merg Lab is highly interdisciplinary with research interests spanning the fields of peptide chemistry, materials chemistry, supramolecular chemistry, materials science, and bioengineering.
Recent Publications
- Tat and other arginine-rich peptides attenuate neuronal activity-induced signaling and gene transcription via extracellular inhibition of NMDA receptors
- Tat and other arginine-rich peptides attenuate neuronal activity-induced signaling and gene transcription via extracellular inhibition of NMDA receptors
- Mesoporous Frameworks Assembled from Amphiphilic Collagen-Mimetic Peptides
- Influence of Linker Design on the Stability, Folding, and Assembly of Tethered Collagen-Mimetic Peptides
- Vibrio cholerae adhesin-derived peptide mediates strong pull-off forces in aqueous high-ionic-strength environments
- Coiled Coil Peptide Tiles: Expanding the Peptide Building Block Design with Multivalent Peptide Macrocycles